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Postmenopausal Hormone Replacement Effects on Autonomic

Enter the shape, color, or imprint of your prescription or OTC drug. Complementary and alternative therapies for the management of menopause-related symptoms: a systematic evidence review (; Structured abstract).

Hormone Replacement Therapy in the Geriatric Patient

HRT (hormone replacement therapy) with estrogen/progestin or estrogen alone has traditionally been the standard of care to alleviate menopausal symptoms and prevent post-menopausal osteoporosis.[1-4] However, in 2002, the shocking results of the Women’s Health Initiative (WHI) study were published, showing that estrogen/progestin HRT snificantly increases risk of breast cancer, heart attack (myocardial infarction) and vein thrombosis.[5] A second WHI study with estrogen HRT (without progestin) on post-menopausal women with prior hysterectomy (surgery that removes the uterus) also found an increased risk of stroke and pulmonary embolism.[6] Both these studies were terminated early because of unacceptable risk-to-benefit ratio.

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