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Interventions All patients were treated with isotretinoin and followed-up in our outpatient clinics after 10 and 20 weeks.

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Also known as 13-cis-retinoic acid, is an oral pharmaceutical drug primarily used to treat severe nodular acne.

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When it strikes during the teen years, it can lead to feelings of self-consciousness, embarrassment and depression.

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The use of Accutane® for acne has become hy controversial, and for very good reasons, but in the beginning it seemed like the answer to every acne sufferer’s prayers.

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