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Effexor is a dual purpose antidepressant released by Wyeth-Ayerst Laboratories and approved by the FDA in October 1997.

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First introduced by Wyeth in 1993, now marketed by Pfizer, it is licensed for the treatment of major depressive disorder (MDD), generalised anxiety disorder (GAD), panic disorder and social phobia.

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A comparative meta-analysis of 12 major antidepressants found that venlafaxine, mirtazapine, escitalopram, and sertraline were snificantly more efficacious than duloxetine, fluoxetine, fluvoxamine, paroxetine, and reboxetine.

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